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Standard fats need to be packaged into chylomicrons. C10 goes straight to the portal vein.
The heart runs continuously and relies on fatty acids for energy. Most MCT (Medium Chain Triglyceride) oils are unpredictable blends: C8 converts rapidly into ketones for 'brain fuel,' while C12 acts like a long-chain fat, getting bogged down in slow digestion and requiring special carriers just to enter the cell.
Pure Tricaprin (C10) possesses distinct metabolic properties that have made it a differentiated focus of cardiovascular metabolic research.
Most MCT oils try to do everything. We chose the one built for the heart.
Your body treats every chain length differently. Pure C10 takes the "Express Lane."
Standard fats need to be packaged into chylomicrons. C10 goes straight to the portal vein.
Unlike long chain fats, C10 is less dependent on the carnitine shuttle, giving it a more direct path into mitochondrial energy metabolism.
C10 is rapidly oxidized for ATP energy, providing a highly efficient, direct fuel source for cardiac tissue.
Blended MCT oils split the job. Pure C10 delivers one focused metabolic pathway with no competing signals from C8 or C12.
We prioritized real, source-linked studies most relevant to cardiovascular health. The strongest direct human evidence today is in TGCV, a rare disorder of impaired intracellular triglyceride breakdown in the heart and coronary arteries.
This is the strongest published human outcomes paper so far. The authors reported long-term survival and durable recovery of heart failure in patients with TGCV treated with tricaprin.
In two patients with TGCV and refractory angina, follow-up coronary CT after tricaprin was associated with visible regression of diffuse coronary plaque, wider vessel lumens, symptom improvement, and better BMIPP imaging.
In a small double blind Phase IIa trial, tricaprin improved a cardiac imaging marker of fat breakdown versus placebo over 8 weeks. This is the best controlled human mechanism study in the literature so far.
This case report used proton MR spectroscopy to show that after 8 weeks of CNT-01, myocardial triglyceride content fell and BMIPP washout improved, giving a second noninvasive readout beyond standard scintigraphy.
In a young man with severe diffuse triple vessel disease, follow up after CABG plus tricaprin showed regression of diffuse lesions, improved myocardial fibrosis imaging, improved BMIPP washout, and clinical stability.
In ATGL knockout mice, tricaprin reduced triglyceride buildup inside the heart and improved left ventricular function. This paper helped establish the biological rationale before the later human studies.
Researchers found that tricaprin reversed many abnormal protein changes linked with cardiac damage and arrhythmia pathways in the TGCV mouse model, strengthening the mechanism story.
In a rat aneurysm model, C10 tricaprin, but not C8 tricaprylin, suppressed aneurysm development, prevented rupture, and improved elastin, collagen, and aortic wall integrity.
Detailed answers from our pharmacist formulation team.
Pure C10. No blend. No dilution. Just the chain length that makes tricaprin different.
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